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Professional Career: Mitchell was signed by the San Francisco 49ers as an undrafted free agent on May 1, 2009. He was waived on September 5, and subsequently signed to the practice squad on September 6. He was released from the practice squad on September 8 and later re-signed to the practice squad on October 13. He was recently signed by the 49ers to a future contract on January 6, 2010.
Collegiate Career: Khalif started his collegiate career at the University of North Carolina before transferring to East Carolina University after his freshman season. During his first year at ECU, he played on the scout team and earned the Rick Bankston Memorial Award, which is given to the defensive unit's top scout team player. He didn't suit up for the Pirates until the 2007 season due to transfer regulations. At the end of the 2007 season, he was named an honorable mention All-Conference USA selection.